Details for gene set NCI_CLASS I PI3K SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NCI_CLASS I PI3K SIGNALING EVENTS
Enrichment Score (ES)	-0.44723132
Normalized Enrichment Score (NES)	-1.8348328
Nominal p-value	0.0
FDR q-value	0.029847082
FWER p-Value	0.4

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PLCG1	1435149_at 1450360_at	8	9.555	0.0227	No
2	FGR	1419526_at 1442804_at	204	5.919	0.0280	No
3	INPPL1	1460394_a_at	349	4.975	0.0333	No
4	FYN	1417558_at 1441647_at 1448765_at	519	4.286	0.0359	No
5	CDK4	1422441_x_at	544	4.192	0.0449	No
6	BLK	1422775_at	610	3.996	0.0515	No
7	PLCG2	1426926_at	843	3.475	0.0492	No
8	HRAS	1422407_s_at 1424132_at	938	3.277	0.0528	No
9	XPO1	1418442_at 1418443_at 1448070_at	1151	2.956	0.0502	No
10	TIAM1	1418057_at 1444373_at 1453887_a_at	1292	2.802	0.0505	No
11	CDKN1A	1421679_a_at 1424638_at	1430	2.662	0.0506	No
12	MALT1	1445068_at 1456126_at 1456429_at	1490	2.604	0.0542	No
13	RASA1	1426476_at 1426477_at 1426478_at 1438998_at	1500	2.593	0.0600	No
14	PPP2R5D	1450560_a_at	1667	2.413	0.0582	No
15	KPNB1	1416925_at 1434357_a_at 1448526_at 1451967_x_at	1733	2.357	0.0609	No
16	ARFIP2	1424240_at 1435498_at	1780	2.323	0.0644	No
17	CDKN2A	1450140_a_at	1811	2.297	0.0685	No
18	EIF4A1	1427058_at 1430980_a_at 1434985_a_at	1943	2.186	0.0678	No
19	CAMK2G	1423941_at 1423942_a_at	1955	2.180	0.0725	No
20	MAF	1435828_at 1437473_at 1444073_at 1447849_s_at 1447945_at 1456060_at	1970	2.170	0.0771	No
21	PPARG	1420715_a_at	2038	2.118	0.0791	No
22	IL2RA	1420691_at 1420692_at	2087	2.083	0.0819	No
23	FOSL1	1417487_at 1417488_at	2333	1.933	0.0753	No
24	E2F1	1417878_at 1431875_a_at 1447840_x_at	2542	1.816	0.0701	No
25	PPP3CC	1420743_a_at 1430025_at	2782	1.725	0.0633	No
26	EIF4G1	1427036_a_at 1427037_at 1438686_at	2802	1.715	0.0665	No
27	SH3BP5	1421922_at 1421923_at 1444346_at	2833	1.704	0.0693	No
28	CD72	1426112_a_at	2883	1.687	0.0711	No
29	SLC3A2	1425364_a_at	2914	1.676	0.0737	No
30	TP53	1426538_a_at 1427739_a_at 1438808_at 1457623_x_at 1459780_at 1459781_x_at	3061	1.619	0.0709	No
31	MAP3K14	1422999_at 1434364_at	3434	1.499	0.0574	No
32	AKT1S1	1428158_at 1437736_at 1452684_at	3440	1.496	0.0608	No
33	YWHAG	1420816_at 1420817_at 1450012_x_at 1459693_x_at	3489	1.477	0.0621	No
34	CD19	1450570_a_at	3704	1.408	0.0557	No
35	HSP90AA1	1426645_at 1437497_a_at 1438902_a_at 1455078_at	3884	1.361	0.0507	No
36	CASP3	1426165_a_at 1430192_at 1449839_at	3970	1.341	0.0500	No
37	CD79A	1418830_at	4303	1.267	0.0378	No
38	PPP5C	1424115_at 1424116_x_at 1451242_a_at	4331	1.262	0.0396	No
39	CALM3	1426710_at 1438825_at 1438826_x_at 1450864_at	4358	1.257	0.0415	No
40	EGR4	1449977_at	4461	1.237	0.0397	No
41	RNF128	1418318_at 1449036_at	4517	1.228	0.0402	No
42	MKNK1	1417630_at 1417631_at 1454119_at	4646	1.202	0.0372	No
43	ELK1	1421896_at 1421897_at 1446390_at	4953	1.143	0.0258	No
44	PTPRC	1422124_a_at 1440165_at	4964	1.140	0.0281	No
45	BTK	1422755_at	4976	1.137	0.0304	No
46	CALM2	1422414_a_at 1423807_a_at	5136	1.110	0.0257	No
47	YWHAB	1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at	5228	1.094	0.0242	No
48	PDE3B	1433694_at	5292	1.084	0.0239	No
49	MAP3K7	1419988_at 1425795_a_at 1426627_at 1449693_at 1455441_at 1458787_at	5318	1.078	0.0253	No
50	IBTK	1434282_at 1439285_at 1454905_at	5359	1.071	0.0261	No
51	IFNG	1425947_at	5363	1.070	0.0285	No
52	RPS6	1453466_at	5451	1.055	0.0271	No
53	AKT1	1416657_at 1425711_a_at 1440950_at 1442759_at	5518	1.047	0.0265	No
54	EIF4EBP1	1417562_at 1417563_at 1434976_x_at	5828	1.006	0.0147	No
55	RAN	1443131_at 1446819_at 1447478_at 1460551_at	5842	1.004	0.0166	No
56	KRAS	1426228_at 1426229_s_at 1434000_at 1451979_at	5870	1.002	0.0177	No
57	UBE2D3	1423112_at 1423113_a_at 1423114_at 1450858_a_at 1450859_s_at 1455479_a_at 1455480_s_at	5934	0.995	0.0172	No
58	COPA	1415706_at 1437274_at	6226	0.954	0.0061	No
59	MAPK1	1419568_at 1426585_s_at 1442876_at 1453104_at	6326	0.939	0.0038	No
60	RPS6KB1	1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at	6539	0.907	-0.0037	No
61	PRKCZ	1418085_at 1449692_at 1454902_at	6548	0.906	-0.0019	No
62	INSR	1421380_at 1450225_at	6601	0.897	-0.0021	No
63	BLNK	1451780_at	6620	0.895	-0.0008	No
64	CD22	1419768_at 1419769_at 1445222_at	7327	0.796	-0.0314	No
65	IL3	1450566_at	7697	0.750	-0.0466	No
66	TSC1	1422043_at 1439989_at 1455252_at	8044	0.703	-0.0608	No
67	BAD	1416582_a_at 1416583_at	8047	0.703	-0.0592	No
68	RHEB	1416636_at	8055	0.702	-0.0578	No
69	RAC1	1423734_at 1437674_at 1451086_s_at	8062	0.701	-0.0564	No
70	FCGR2B	1435476_a_at 1435477_s_at 1447622_at 1451941_a_at 1455332_x_at	8353	0.663	-0.0682	No
71	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	9038	0.581	-0.0983	No
72	ARHGEF6	1429012_at 1442292_at	9073	0.578	-0.0984	No
73	TBX21	1449361_at	9537	0.523	-0.1185	No
74	AP2A1	1460724_at	9775	0.496	-0.1282	No
75	YWHAZ	1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at	9868	0.485	-0.1313	No
76	PTEN	1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at	10105	0.457	-0.1410	No
77	CYLD	1429617_at 1429618_at 1445213_at	10365	0.433	-0.1519	No
78	NFKBIB	1421266_s_at 1446718_at	10476	0.420	-0.1560	No
79	IL4	1449864_at	10496	0.418	-0.1558	No
80	CLTA	1421062_s_at 1434540_a_at 1444328_at	10538	0.415	-0.1567	No
81	DOK1	1417790_at	10940	0.367	-0.1743	No
82	AKAP5	1447301_at	11001	0.361	-0.1762	No
83	CSF2	1427429_at	11147	0.346	-0.1820	No
84	RIPK2	1421236_at 1450173_at	11319	0.326	-0.1891	No
85	ZAP70	1422701_at 1439749_at 1440178_x_at	11479	0.306	-0.1957	No
86	PLD2	1417237_at 1457252_x_at	11555	0.299	-0.1984	No
87	SYK	1418261_at 1418262_at 1425797_a_at 1457239_at	11646	0.289	-0.2019	No
88	TNF	1419607_at	11771	0.274	-0.2069	No
89	YWHAQ	1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at	12338	0.217	-0.2325	No
90	SRC	1423240_at 1450918_s_at	12634	0.185	-0.2456	No
91	TBC1D4	1435292_at 1455903_at	12653	0.182	-0.2460	No
92	PLEKHA1	1417965_at 1443111_at	12832	0.161	-0.2538	No
93	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	13226	0.116	-0.2716	No
94	JUN	1417409_at 1448694_at	13265	0.110	-0.2731	No
95	PTGS2	1417262_at 1417263_at	13435	0.089	-0.2807	No
96	RAP1A	1424139_at	13464	0.086	-0.2817	No
97	POU2F2	1427713_x_at 1427725_a_at	13563	0.074	-0.2861	No
98	YES1	1418470_at 1449090_a_at 1456843_at 1458878_at	14075	0.006	-0.3096	No
99	ARHGEF7	1424482_at 1449066_a_at	14084	0.004	-0.3099	No
100	SFN	1448612_at	14234	-0.019	-0.3168	No
101	PTPRK	1423277_at 1423278_at 1431680_a_at 1441276_at 1441277_s_at 1441644_at 1443491_at 1443699_at 1444763_at	14337	-0.034	-0.3214	No
102	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	14353	-0.036	-0.3220	No
103	AP2M1	1442227_at 1442429_at 1443338_at 1450894_a_at 1457122_at	14454	-0.052	-0.3265	No
104	SHC1	1422853_at 1422854_at	14924	-0.125	-0.3478	No
105	PIK3CA	1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at	14972	-0.133	-0.3496	No
106	PRKCE	1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at	15005	-0.138	-0.3507	No
107	ATM	1421205_at 1428830_at	15042	-0.145	-0.3520	No
108	KPNA1	1419548_at 1449503_at 1449504_at 1460260_s_at	15162	-0.164	-0.3571	No
109	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	15248	-0.177	-0.3606	No
110	PAG1	1423002_at 1440033_at 1443319_at 1456403_at	15557	-0.231	-0.3742	No
111	PIM1	1423006_at 1435458_at	15787	-0.279	-0.3841	No
112	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	15983	-0.319	-0.3923	No
113	FKBP1A	1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at	16008	-0.325	-0.3926	No
114	GSK3A	1435638_at	16180	-0.365	-0.3996	No
115	IRS1	1423104_at	16185	-0.367	-0.3989	No
116	IRF4	1421173_at 1421174_at	16277	-0.392	-0.4022	No
117	CD40LG	1422283_at	16403	-0.421	-0.4069	No
118	REL	1420710_at	16635	-0.480	-0.4164	No
119	HCK	1446553_at 1449455_at	16712	-0.502	-0.4187	No
120	NFATC1	1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at	16786	-0.526	-0.4208	No
121	PRKACA	1447720_x_at 1450519_a_at	16824	-0.536	-0.4212	No
122	MAP2K1	1416351_at	16935	-0.572	-0.4249	No
123	CLTB	1453063_at 1456797_at 1460740_at	16993	-0.593	-0.4261	No
124	FOXP3	1420765_a_at 1457082_at	17059	-0.612	-0.4276	No
125	PTPN1	1417068_a_at 1438670_at	17061	-0.612	-0.4262	No
126	FASLG	1418803_a_at 1449235_at	17094	-0.623	-0.4261	No
127	IKBKB	1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at	17210	-0.664	-0.4298	No
128	RAF1	1416078_s_at 1425419_a_at	17235	-0.675	-0.4293	No
129	RHOA	1437628_s_at	17319	-0.701	-0.4314	No
130	ERC1	1421501_a_at 1424247_at 1441493_at 1444356_at 1451279_at	17322	-0.702	-0.4298	No
131	EIF4E	1450909_at 1457489_at 1459371_at	17356	-0.717	-0.4296	No
132	FBXW11	1425461_at 1425462_at 1437468_x_at 1438336_at 1443010_at 1447294_at 1457485_at	17437	-0.752	-0.4315	No
133	GRB2	1418508_a_at 1449111_a_at	17468	-0.764	-0.4310	No
134	AKT3	1422078_at 1435260_at 1435879_at 1443222_at 1460307_at	17472	-0.767	-0.4293	No
135	ARFGAP1	1427245_at 1445067_at	17500	-0.777	-0.4287	No
136	CALM1	1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at	17505	-0.779	-0.4270	No
137	POU2F1	1419716_a_at 1427695_a_at 1427835_at	17578	-0.808	-0.4284	No
138	TSC2	1452105_a_at	17608	-0.823	-0.4277	No
139	ARF1	1420920_a_at 1426390_a_at	17692	-0.854	-0.4295	No
140	MAPK9	1421876_at 1421877_at 1421878_at	17782	-0.895	-0.4314	No
141	CHUK	1417091_at 1428210_s_at 1451383_a_at	17804	-0.903	-0.4302	No
142	CSNK1A1	1424827_a_at 1428537_at 1430529_at 1451497_at 1456216_at	17814	-0.908	-0.4284	No
143	ARRB2	1426239_s_at 1451987_at	17849	-0.929	-0.4277	No
144	MEF2D	1421388_at 1434487_at 1436642_x_at 1437300_at 1458901_at	17877	-0.936	-0.4267	No
145	PPP3CA	1426401_at 1438478_a_at 1440051_at 1452056_s_at 1458495_at	17912	-0.953	-0.4260	No
146	SLC2A4	1415958_at 1415959_at	17966	-0.969	-0.4261	No
147	NFKBIA	1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at	18087	-1.008	-0.4292	No
148	CAMK4	1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at	18098	-1.010	-0.4272	No
149	FKBP8	1416113_at	18186	-1.035	-0.4287	No
150	PRKDC	1451576_at	18211	-1.043	-0.4273	No
151	ARF5	1422807_at	18252	-1.061	-0.4266	No
152	NUP214	1434351_at 1456503_at 1457815_at	18505	-1.172	-0.4354	No
153	NFKB2	1425902_a_at 1429128_x_at	18571	-1.202	-0.4355	No
154	ITK	1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at	18604	-1.214	-0.4340	No
155	MAP3K8	1419208_at	18698	-1.260	-0.4353	No
156	SOS1	1421884_at 1421885_at 1421886_at	18731	-1.279	-0.4336	No
157	PLEKHA2	1417288_at 1417289_at	19027	-1.449	-0.4437	Yes
158	PRKAB1	1424119_at 1452457_a_at	19067	-1.478	-0.4420	Yes
159	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	19071	-1.481	-0.4385	Yes
160	EEF2	1424736_at 1440784_at 1441414_at	19246	-1.592	-0.4427	Yes
161	FRAP1	1417592_at 1436267_a_at 1446185_at 1459625_at	19266	-1.605	-0.4397	Yes
162	CARD11	1430257_at 1435996_at	19280	-1.617	-0.4364	Yes
163	MAPK3	1427060_at	19380	-1.691	-0.4369	Yes
164	IL5	1425546_a_at 1442049_at 1450550_at	19394	-1.700	-0.4334	Yes
165	PRKCH	1422079_at 1434248_at	19474	-1.756	-0.4328	Yes
166	NRAS	1422688_a_at 1454060_a_at	19506	-1.778	-0.4299	Yes
167	NFATC2	1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at	19581	-1.851	-0.4289	Yes
168	DAPP1	1421936_at 1421937_at 1447337_at	19606	-1.880	-0.4254	Yes
169	IKBKG	1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at	19699	-1.951	-0.4250	Yes
170	YWHAE	1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at	19732	-1.981	-0.4217	Yes
171	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	19756	-1.997	-0.4179	Yes
172	ARF6	1418822_a_at 1418823_at 1418824_at	19821	-2.038	-0.4159	Yes
173	CBLB	1437304_at 1455082_at 1458469_at	19947	-2.123	-0.4166	Yes
174	YWHAH	1416004_at	20026	-2.200	-0.4149	Yes
175	ITCH	1415769_at 1431316_at 1459332_at	20078	-2.248	-0.4118	Yes
176	CD4	1419696_at 1427779_a_at	20116	-2.283	-0.4080	Yes
177	CTLA4	1419334_at	20241	-2.409	-0.4079	Yes
178	MDM2	1423605_a_at 1427718_a_at 1457929_at	20268	-2.435	-0.4032	Yes
179	GOSR2	1419371_s_at 1419372_at	20324	-2.498	-0.3997	Yes
180	NFKB1	1427705_a_at 1442949_at	20346	-2.528	-0.3946	Yes
181	BCL3	1418133_at	20382	-2.577	-0.3900	Yes
182	CASP9	1426125_a_at 1437537_at 1457816_at	20601	-2.861	-0.3931	Yes
183	PTPN6	1456694_x_at 1460188_at	20681	-2.991	-0.3896	Yes
184	GATA3	1448886_at	20751	-3.097	-0.3853	Yes
185	MAPKAP1	1417284_at 1427212_at 1442692_at	20776	-3.149	-0.3788	Yes
186	RELA	1419536_a_at	20799	-3.184	-0.3721	Yes
187	FOS	1423100_at	20955	-3.496	-0.3708	Yes
188	EP300	1434765_at	20959	-3.504	-0.3625	Yes
189	PPP3CB	1427468_at 1428473_at 1428474_at 1433835_at 1446149_at 1459378_at	20987	-3.561	-0.3552	Yes
190	GBF1	1415709_s_at 1415757_at 1432677_at 1438207_at	21042	-3.685	-0.3488	Yes
191	BIRC2	1418854_at	21087	-3.757	-0.3417	Yes
192	VAV1	1422932_a_at	21119	-3.839	-0.3339	Yes
193	PDPK1	1415729_at 1416501_at 1459775_at 1459776_x_at	21147	-3.899	-0.3257	Yes
194	TNFAIP3	1433699_at 1450829_at	21180	-3.976	-0.3176	Yes
195	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	21224	-4.102	-0.3097	Yes
196	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	21309	-4.363	-0.3030	Yes
197	RELB	1417856_at	21351	-4.570	-0.2939	Yes
198	GGA3	1438008_at	21359	-4.589	-0.2832	Yes
199	PRKCQ	1426044_a_at	21404	-4.723	-0.2738	Yes
200	JUNB	1415899_at	21503	-5.184	-0.2658	Yes
201	CSK	1423518_at 1439744_at	21538	-5.342	-0.2545	Yes
202	CD79B	1417640_at	21546	-5.396	-0.2418	Yes
203	NR4A1	1416505_at	21561	-5.542	-0.2291	Yes
204	MAP3K1	1424850_at	21563	-5.558	-0.2157	Yes
205	TNFRSF1A	1417291_at	21597	-5.736	-0.2034	Yes
206	NFATC3	1419976_s_at 1452497_a_at	21671	-6.290	-0.1916	Yes
207	PRKCD	1422847_a_at 1442256_at	21741	-6.917	-0.1781	Yes
208	DGKA	1418578_at	21744	-6.953	-0.1614	Yes
209	ETS1	1422027_a_at 1422028_a_at 1426725_s_at 1452163_at	21749	-7.027	-0.1447	Yes
210	CSNK2A1	1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at	21816	-7.560	-0.1295	Yes
211	CDKN1B	1419497_at 1434045_at	21856	-7.819	-0.1124	Yes
212	EGR1	1417065_at	21860	-7.832	-0.0937	Yes
213	GSK3B	1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at	21861	-7.833	-0.0748	Yes
214	AKT2	1421324_a_at 1424480_s_at 1455703_at	21877	-7.894	-0.0564	Yes
215	VAV2	1421272_at 1435065_x_at 1435244_at 1458758_at	21902	-8.090	-0.0380	Yes
216	EGR2	1427682_a_at 1427683_at	21904	-8.113	-0.0185	Yes
217	EGR3	1421486_at 1436329_at	21913	-8.258	0.0011	Yes